McKesson Confiderm 3.5C XL Nitrile Exam Gloves

For home caregivers, home health aides, and medical professionals who go through examination gloves daily, the McKesson Confiderm 3.5C sets a high standard for what a reliable nitrile exam glove should deliver. At 3.5 mil thickness with a textured fingertip surface, it strikes the right balance between barrier protection and tactile sensitivity — thick enough for meaningful puncture resistance, thin enough to feel what you are touching. Powder-free and latex-free construction eliminates two of the most common causes of skin irritation and allergic reactions in frequent glove users. The XL size fits larger hands correctly without the bunching, restriction, or finger-gap that occurs when a smaller glove is stretched to fit — and with 150 gloves per box, it is sized for the volume demands of daily home care and clinical use.

Who This Is For

• Home health aides, CNAs, and family caregivers who perform personal care tasks — wound care, catheter management, ostomy care, incontinence care — and need a reliable, comfortable daily-use exam glove in XL
• Nurses and clinical staff in oncology, infusion, or compounding settings who require a chemotherapy-tested glove for handling hazardous drugs
• Anyone with larger hands who has struggled with standard or large gloves that are too short in the fingers, too tight across the palm, or restrict circulation during extended wear
• Home caregivers managing wound care, medication administration, or infection control for a loved one who needs a professional-grade glove rather than a consumer alternative
• Facilities and home health agencies stocking XL gloves for staff with larger hand sizes who cannot use standard large gloves comfortably

Key Features

• 3.5 Mil Nitrile Construction — Barrier Protection with Tactile Feel: The 3.5 mil thickness provides a meaningful barrier against blood, bodily fluids, disinfectants, and a broad range of chemicals encountered in caregiving and clinical settings. Nitrile's puncture resistance is significantly higher than latex at equivalent thickness, and unlike latex, nitrile does not degrade rapidly with exposure to oils and many chemical agents. The 3.5 mil profile keeps the glove thin enough to maintain the tactile sensitivity required for procedures where feel matters — catheter insertion, wound assessment, medication preparation.
• Chemo-Tested to ASTM D6978-05: The Confiderm 3.5C is tested for use with chemotherapy drugs per ASTM D6978-05 — the standard test method for resistance of protective clothing materials to permeation by liquids or gases. This testing confirms the glove provides a barrier against penetration by specific chemotherapy agents under defined test conditions. For caregivers administering oral chemotherapy at home, nurses handling hazardous drugs, or compounding pharmacy staff, this rating is a clinical requirement. Note: gloves used for chemotherapy protection must be selected based on the specific drugs being handled — review drug labeling or safety data sheets to confirm adequacy for your specific application.
• Textured Fingertips — Grip and Sensitivity in Wet Conditions: The fingertip texture provides tactile grip on wet, slippery, or small surfaces that a smooth glove would struggle to hold. This matters practically during dressing changes where gauze and tape are handled with wet gloves, during medication management where small pills or syringes must be grasped precisely, and during personal care tasks where grip is needed regardless of moisture. The texture does not compromise tactile sensitivity — users can feel through the fingertips reliably during assessment and fine-motor tasks.
• Powder-Free — No Residue, No Contamination Risk: Powdered gloves leave cornstarch residue on surfaces, instruments, and wounds — a known source of inflammation and contamination in wound care and surgical settings. Powder-free construction eliminates this risk entirely and is the clinical standard for exam gloves in most healthcare settings. Powder-free gloves are also significantly less likely to cause contact dermatitis in frequent users, as powder is a major carrier of latex proteins and other sensitizing agents.
• Latex-Free — Safe for Latex-Sensitive Users and Patients: True latex allergy affects a meaningful percentage of healthcare workers and patients, and reactions can range from contact dermatitis to anaphylaxis in sensitized individuals. The Confiderm 3.5C is not made with natural rubber latex, eliminating this risk for both the wearer and any patient whose skin the glove contacts. This is particularly important in home care settings where the patient's latex sensitivity may not always be documented or known to every caregiver.
• Beaded Cuff — Secure Fit and Controlled Removal: The beaded cuff runs around the wrist opening of the glove, providing two functions: it creates a rolled edge that prevents the glove from rolling down the wrist during use, maintaining consistent coverage; and it provides a defined edge for controlled removal using the standard glove removal technique — pulling from the beaded cuff rather than touching the contaminated outer surface. The standard cuff length of approximately 9.6 inches covers the wrist adequately for most caregiving tasks.
• Ambidextrous Design — XL Fits Either Hand: The gloves are cut identically for left and right hands, so there is no sorting required when donning in a hurry. For caregivers performing frequent glove changes throughout a shift, ambidextrous design meaningfully reduces the time and attention required for each change.
• 150 Gloves Per Box — Volume for Daily Use: A single box provides 150 individual gloves — enough for sustained daily use in a home care setting where a caregiver might go through 6–10 pairs per day across multiple care tasks. Buying by the box rather than in smaller quantities significantly reduces per-glove cost for high-volume users.

Glove Sizing — Measure for Correct XL Fit

Correct glove size is important for both protection and usability. A glove that is too small tears more easily, restricts circulation during extended wear, and reduces tactile sensitivity. A glove that is too large bunches at the fingers, reduces grip, and can slip during procedures. To find your correct size, measure the circumference of your dominant hand at the widest part across the palm (excluding the thumb):

Technical Specifications

Important Safety Notice

Gloves used for protection against chemotherapy drug exposure must be selected specifically for the type of chemicals being handled. Review drug labeling or safety data sheets for the chemicals being used to determine an adequate level of protection for the intended use. These gloves may puncture or tear if donned improperly or if in contact with sharp fingernails or objects such as finger rings. Test results for specific chemotherapy drugs are available upon request by contacting McKesson directly.