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Authorized Re-Seller - Serving the Continental U.S. - Now offering FREE shipping on all orders over $95!
Authorized Re-Seller - Serving the Continental U.S. - Now offering FREE shipping on all orders over $95!

2XL Briefs

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mckesson xxl super briefs
$13.25 - $46.99
$13.25 - $46.99
$13.25 - $46.99
$13.25

McKesson Super Absorbent Briefs – XXL

in stock

McKesson Super Absorbent Briefs – XXL Brand: McKesson Medical Supplies Product Style: Unisex Tab-Style Open Brief Desi...

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$13.25 - $46.99
$13.25 - $46.99
$13.25 - $46.99
$13.25
Seni Classic Plus adult diaper packaging on a white background
$28.00 - $90.99
$28.00 - $90.99
$28.00 - $90.99
$28.00

Seni® Classic Plus Incontinence Briefs – Large (Unisex)

in stock

Seni Classic Plus Briefs – Large Model: Seni® Classic Plus Breathable Brief Series (SKU # S-LA25-BC2) Availability...

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$28.00 - $90.99
$28.00 - $90.99
$28.00 - $90.99
$28.00
Package of Seni Classic Plus briefs on a white background
$22.49 - $89.99
$22.49 - $89.99
$22.49 - $89.99
$22.49

Seni® Classic Plus Incontinence Briefs – Regular (Unisex)

in stock

Seni Classic Plus Briefs – Regular Model: Seni® Classic Plus Breathable Brief Series (SKU # S-RE25-BC2) Availabili...

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$22.49 - $89.99
$22.49 - $89.99
$22.49 - $89.99
$22.49
Box of Tranquility Premium Overnight Underwear with packaging details on a white background
$21.29 - $76.99
$21.29 - $76.99
$21.29 - $76.99
$21.29

Tranquility Premium OverNight Underwear 2x - Heavy Absorbency Adult Pull-Ons

in stock

Tranquility® Premium OverNight™ Underwear – 2X-Large Model: Tranquility® Premium OverNight™ Protective Underwear Series (#2118) Av...

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$21.29 - $76.99
$21.29 - $76.99
$21.29 - $76.99
$21.29
Tena comfort pants
$6.79 - $70.99
$6.79 - $70.99
$6.79 - $70.99
$6.79

TENA ProSkin Comfort Pants 2XL/3XL Orange Waistband

in stock

TENA ProSkin Comfort Pants – 2X-Large / 3X-Large (Reusable) Model: TENA ProSkin™ Premium Seamless Knit Fixation Series (Ma...

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$6.79 - $70.99
$6.79 - $70.99
$6.79 - $70.99
$6.79
Pack of Cardinal Health Quilted Stretch Briefs on a white background
$16.49 - $59.99
$16.49 - $59.99
$16.49 - $59.99
$16.49

Cardinal Health Wings Ultra Quilted Stretch Adult Briefs (Size 3)

in stock

The Cardinal Health Wings™ Ultra Quilted Stretch Adult Briefs (Size 3) represent a premier, maximum-tier bariatric incontinence solution specifical...

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$16.49 - $59.99
$16.49 - $59.99
$16.49 - $59.99
$16.49
White boxer briefs with a green waistband on a white background
$2.39 - $139.99
$2.39 - $139.99
$2.39 - $139.99
$2.39

Wings™ Maternity Knit Pants - 2X-Large / 3X-Large

in stock

Wings™ Maternity Knit Pants – 2X-Large / 3X-Large Model: Wings™ Maternity Seamless High-Density Series (Manufacturer #707M...

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$2.39 - $139.99
$2.39 - $139.99
$2.39 - $139.99
$2.39
TENA stretch brief packaging with a single brief in front on a white background
$47.99 - $74.49
$47.99 - $74.49
$47.99 - $74.49
$47.99

TENA Stretch Plus Incontinence Briefs, 2X-Large (64 to 70 Inch)

in stock

TENA Stretch Plus Briefs – 2X-Large Model: TENA® Stretch™ Plus Hybrid Series (SKU # 61090) Availability: In Stock ...

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$47.99 - $74.49
$47.99 - $74.49
$47.99 - $74.49
$47.99
tena proskin stretch briefs
$41.99 - $89.99
$41.99 - $89.99
$41.99 - $89.99
$41.99

TENA ProSkin Stretch Ultra Briefs 2X-Large

in stock

TENA ProSkin Stretch Ultra Briefs – 2X-Large Brand: TENA® ProSkin Stretch Ultra Series Product Style: Unisex Hybrid Ta...

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$41.99 - $89.99
$41.99 - $89.99
$41.99 - $89.99
$41.99
TENA Complete+Care Ultra briefs packaging with a single brief displayed on a white background
$38.99 - $65.99
$38.99 - $65.99
$38.99 - $65.99
$38.99

TENA Complete + Care Ultra Briefs 2X-Large - Bariatric Moderate Absorbency

in stock

TENA Complete +Care Ultra Briefs – 2X-Large Bariatric Brand: TENA® Complete +Care Ultra Series Product Style: Unisex P...

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$38.99 - $65.99
$38.99 - $65.99
$38.99 - $65.99
$38.99
Package of Prevail Nu-Fit daily briefs with features highlighted on a white background
$13.99 - $50.99
$13.99 - $50.99
$13.99 - $50.99
$13.99

Prevail® Nu-Fit® adult Incontinence Brief 2X-Large unisex Disposable Heavy Absorbency

in stock

Prevail Nu-Fit Adult Briefs – 2X-Large Model: Prevail® Nu-Fit® Bariatric Open Brief Series Availability: In Stock ...

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$13.99 - $50.99
$13.99 - $50.99
$13.99 - $50.99
$13.99
Package of McKesson Bariatric Ultra Plus Stretch Briefs on a white background
$24.99 - $94.99
$24.99 - $94.99
$24.99 - $94.99
$24.99

McKesson Ultra Plus Stretch Briefs – 2X/3X-Large

in stock

McKesson Ultra Plus Stretch Briefs – 2X/3X-Large Brand: McKesson Medical Supplies Product Style: Unisex Tab-Style Open...

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$24.99 - $94.99
$24.99 - $94.99
$24.99 - $94.99
$24.99
Box of McKesson Ultra Briefs XXL on a white background
$12.99 - $51.49
$12.99 - $51.49
$12.99 - $51.49
$12.99

McKesson Ultra Absorbent Briefs – XX-Large (63–69")

in stock

McKesson Ultra Absorbent Briefs – XX-Large Brand: McKesson Medical Supplies Product Style: Unisex Tab-Style Open Brief...

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$12.99 - $51.49
$12.99 - $51.49
$12.99 - $51.49
$12.99
Attends Sleep Comfort premium overnight underwear packaging on a white background
$21.99 - $67.99
$21.99 - $67.99
$21.99 - $67.99
$21.99

Attends Sleep Comfort Premium Overnight Underwear 2X-Large

in stock

Attends Sleep Comfort Premium Overnight Underwear – 2XL Model: Attends® Sleep Comfort™ Premium Overnight Underwear Series ...

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$21.99 - $67.99
$21.99 - $67.99
$21.99 - $67.99
$21.99
Attends Bariatric Briefs packaging on a white background
$15.99 - $48.99
$15.99 - $48.99
$15.99 - $48.99
$15.99

Attends Bariatric Briefs – Heavy Absorbency – 2X-Large (63"–70")

in stock

Attends Bariatric Premium Briefs – 2X-Large Model: Attends® Bariatric Brief with SecureGrip™ (#DD50) Availability:...

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$15.99 - $48.99
$15.99 - $48.99
$15.99 - $48.99
$15.99
Attends bariatric underwear packaging with a sample underwear on a white background
$18.99 - $58.99
$18.99 - $58.99
$18.99 - $58.99
$18.99

Attends Bariatric Pull-On Underwear - Heavy Absorbency, 2X-Large

in stock

Attends Bariatric Premium Protective Underwear – 2X-Large Model: Attends® Bariatric Protective Pull-Ons Series (#AU50) ...

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$18.99 - $58.99
$18.99 - $58.99
$18.99 - $58.99
$18.99
Pack of Tranquility SmartCore disposable briefs in 2XL size on a white background
$21.59 - $74.99
$21.59 - $74.99
$21.59 - $74.99
$21.59

Tranquility SmartCore Disposable Brief 2XL - Heavy Absorbency Tab-Style Adult Brief

in stock

Tranquility® SmartCore™ Disposable Briefs – 2X-Large Model: Tranquility® SmartCore™ Disposable Brief Series (#2315) Availability: ...

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$21.59 - $74.99
$21.59 - $74.99
$21.59 - $74.99
$21.59
Absorbent Underwear Tranquility® Premium DayTime™ Pull On
$23.99 - $73.99
$23.99 - $73.99
$23.99 - $73.99
$23.99

Tranquility Premium DayTime Underwear 2XL - Heavy Absorbency Pull-On Brief

in stock

All-Day Confidence with a Slimmer, Discreet ProfileThe Tranquility® Premium DayTime™ Underwear provides the perfect balance of heavy protection and...

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$23.99 - $73.99
$23.99 - $73.99
$23.99 - $73.99
$23.99
Pack of Tranquility essential underwear with teal and white design on a white background
$17.76 - $63.79
$17.76 - $63.79
$17.76 - $63.79
$17.76

Tranquility Essential Underwear 2XL - Heavy Absorbency Pull-On Brief

in stock

Tranquility® Essential Premium Overnight Underwear – 2X-Large Model: Tranquility® Essential Protective Underwear Series (#2608) Av...

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$17.76 - $63.79
$17.76 - $63.79
$17.76 - $63.79
$17.76
Incontinence Brief Tranquility® Essential Adult 2X-Large Unisex Disposable Heavy Absorbency
$26.49 - $76.99
$26.49 - $76.99
$26.49 - $76.99
$26.49

Tranquility Essential Breathable Briefs 2XL - Heavy Absorbency Tab-Style Brief

in stock

Tranquility® Essential Breathable Briefs – 2X-Large Model: Tranquility® Essential Breathable Brief Series (60"–80" Fitment) Availa...

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$26.49 - $76.99
$26.49 - $76.99
$26.49 - $76.99
$26.49

When a standard large brief no longer provides the right fit, 2XL adult incontinence briefs offer the step up in coverage and comfort that makes a real difference. For caregivers, family members, and individuals who need a wider, more secure fit without sacrificing absorbency or softness, our 2XL collection brings together trusted brands and a range of options to suit everyday needs.

At EnhDme, we've curated our 2XL brief collection with quality and reliability in mind. Whether you're looking for breathable daytime protection, heavy overnight absorbency, or a tab-style brief with refastenable closures for easy adjustments, you'll find options here from brands built specifically for extended, comfortable wear at this size.

Did you know? Proper sizing is one of the most important factors in leak prevention. A brief that fits well — snug at the waist and legs without being restrictive — performs significantly better than one that's too small or too large, regardless of absorbency level.

Our 2XL briefs are sized to fit waist and hip measurements of approximately 55"–80" depending on the brand — always check the individual product size guide to confirm the best fit. With absorbency options ranging from moderate to maximum, and features like wetness indicators, odor control, and skin-friendly materials, you'll find the right brief for any routine. Orders over $95 ship free, so stocking up is straightforward and cost-effective.

What You'll Find in This Collection

  • Disposable tab-style briefs
  • Moderate absorbency briefs
  • Heavy absorbency briefs
  • Maximum absorbency briefs
  • Overnight / extended-wear briefs
  • Breathable side panel briefs
  • Odor-control briefs
  • Latex-free & sensitive skin options

🚚 Free shipping on orders over $95 — EnhDme

2XL Briefs

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