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Authorized Re-Seller - Serving the Continental U.S. - Now offering FREE shipping on all orders over $95!
Authorized Re-Seller - Serving the Continental U.S. - Now offering FREE shipping on all orders over $95!

Large Briefs

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$39.99 - $126.99
$39.99 - $126.99
$39.99 - $126.99
$39.99

MoliCare Premium Elastic 10D – Heavy Absorbency Briefs (Large)

Only 4 left!

MoliCare Premium Elastic 10D Briefs – Large Brand: MoliCare / HARTMANN Product Style: Unisex Disposable Brief with Ela...

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$39.99 - $126.99
$39.99 - $126.99
$39.99 - $126.99
$39.99
Package of Prevail overnight underwear on a white background
$14.29 - $47.99
$14.29 - $47.99
$14.29 - $47.99
$14.29

Prevail® Overnight Pull On Underwear Large unisex Heavy Absorbency

in stock

  Prevail Overnight Absorbency unisex Underwear Prevail® Overnight Absorbency unisex Underwear is designed for individuals who need **overnight or ...

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$14.29 - $47.99
$14.29 - $47.99
$14.29 - $47.99
$14.29
Package of Prevail Per-Fit daily undergarments with purple and blue design
$12.49 - $51.49
$12.49 - $51.49
$12.49 - $51.49
$12.49

Prevail Per-Fit Women's Absorbent Underwear - Large, Moderate

in stock

Prevail Per-Fit Women's Protective Underwear Prevail Per-Fit Women's Protective Underwear is designed for women who prefer the familiar look and f...

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$12.49 - $51.49
$12.49 - $51.49
$12.49 - $51.49
$12.49
Pack of McKesson women's premium discreet underwear with packaging details.
$14.99 - $54.99
$14.99 - $54.99
$14.99 - $54.99
$14.99

McKesson Premium Discreet Women's Absorbent Underwear, Maximum, Large

in stock

McKesson Premium Discreet Women's Underwear – Large Brand: McKesson Medical Supplies Product Style: Women's Disposable...

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$14.99 - $54.99
$14.99 - $54.99
$14.99 - $54.99
$14.99
Gray boxer briefs worn by a person on a white background
$38.99 - $119.99
$38.99 - $119.99
$38.99 - $119.99
$38.99

Nexwear Men's Absorbent Underwear – Large (Gray)

in stock

Nexwear Men's Pull-On Underwear offers a discreet and reliable solution for daily protection and comfort. Designed specifically for the male anatom...

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$38.99 - $119.99
$38.99 - $119.99
$38.99 - $119.99
$38.99
Package of McKesson Ultra Briefs on a white background
$7.39 - $46.99
$7.39
$13.99 - $46.99
$13.99 - $46.99
$13.99

McKesson Ultra Briefs Large Ultra Absorbency

in stock

McKesson Ultra Incontinence Briefs – Large Brand: McKesson Medical Supplies Product Style: Unisex Tab-Style Open Brief...

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$7.39 - $46.99
$7.39
$13.99 - $46.99
$13.99 - $46.99
$13.99
Package of McKesson Super Briefs on a white background
$12.79 - $39.99
$12.79 - $39.99
$12.79 - $39.99
$12.79

McKesson Super Brief Large

in stock

McKesson Super Incontinence Briefs (Large) Model: McKesson Super Adult Brief Series Product Style: Unisex Tab-Style Op...

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$12.79 - $39.99
$12.79 - $39.99
$12.79 - $39.99
$12.79
extended wear underwear
$15.00 - $52.99
$15.00 - $52.99
$15.00 - $52.99
$15.00

McKesson Extended Wear Absorbent Underwear – Large

in stock

McKesson Extended Wear Absorbent Underwear – Large Brand: McKesson Medical Supplies Product Style: Unisex Pull-On Disp...

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$15.00 - $52.99
$15.00 - $52.99
$15.00 - $52.99
$15.00
Cardinal Health, adult Briefs, Wings™ Plus, Large, 45" - 58"
$14.99 - $48.99
$14.99 - $48.99
$14.99 - $48.99
$14.99

Cardinal Support day-to-day Wings™ Plus adult Briefs, Large (45"–58")

in stock

Wings Plus Adult Briefs – Large Brand: Cardinal Health Product Style: Unisex Tab-Style Open Brief Design Hea...

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$14.99 - $48.99
$14.99 - $48.99
$14.99 - $48.99
$14.99
adult incontinence briefs
$12.99 - $46.99
$12.99 - $46.99
$12.99 - $46.99
$12.99

Cardinal Support day-to-day Wings™ Basic Quilted Adult Briefs, Large (45"–58")

in stock

Wings Basic Quilted Adult Briefs – Large Brand: Cardinal Health Product Style: Unisex Tab-Style Open Brief Design ...

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$12.99 - $46.99
$12.99 - $46.99
$12.99 - $46.99
$12.99
Cardinal Health Sure Care Super Protective Underwear – Large, 44"–54"
$39.99 - $159.99
$39.99 - $159.99
$39.99
$19.99 - $73.99
$19.99 - $73.99
$19.99

Cardinal Sure Care Super Protective Underwear – Large, 44"–54"

in stock

Cardinal Sure Care Super Protective Underwear – Large Brand: Cardinal Health Product Style: Unisex Pull-On Disposable ...

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$39.99 - $159.99
$39.99 - $159.99
$39.99
$19.99 - $73.99
$19.99 - $73.99
$19.99
Attends briefs packaging with a white background
$19.00 - $49.99
$19.00 - $49.99
$19.00 - $49.99
$19.00

Attends® Incontinence Briefs Large (44"–58" Waist/Hip)

in stock

Attends Heavy Absorbency Premium Briefs – Large Model: Attends® Maximum Protection Open Briefs (Large) Availabilit...

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$19.00 - $49.99
$19.00 - $49.99
$19.00 - $49.99
$19.00
Attends briefs packaging with a single brief displayed on a white background
$21.99 - $62.99
$21.99 - $62.99
$21.99 - $62.99
$21.99

Attends Care Advanced Incontinence Briefs - Heavy Absorbency, Large

in stock

Attends DermaDry Plus Premium Briefs – Large Model: Attends® DermaDry™ Plus Heavy Incontinence Briefs (#DDP30) Ava...

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$21.99 - $62.99
$21.99 - $62.99
$21.99 - $62.99
$21.99
Attends Briefs packaging with a sample brief on a white background
$54.99 - $54.99
$54.99
$54.99 - $54.99
$54.99

Attends Care Advanced Adult Incontinence Brief - Heavy Absorbency

in stock

Attends Care Advanced Heavy Protection Briefs – Large Model: Attends® Care Advanced Series (SKU # DDP30) Availability: In Stock – Unisex Tab-Sty...

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$54.99 - $54.99
$54.99
$54.99 - $54.99
$54.99
Package of Attends extra heavy absorbency underwear on a white background
$15.99 - $43.99
$15.99 - $43.99
$15.99 - $43.99
$15.99

Attends Care Adult Absorbent Underwear Large

in stock

Attends Care Protective Underwear – Large Model: Attends® Care Protective Underwear (#APV30) Availability: In Stoc...

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$15.99 - $43.99
$15.99 - $43.99
$15.99 - $43.99
$15.99
Stack of white diaper with textured top on a white background
$22.79 - $64.80
$22.79 - $64.80
$22.79 - $64.80
$22.79

Attends Adult Absorbent Underwear Large

in stock

Attends Maximum Protective Underwear – Large Model: Attends® Maximum Protective Underwear Series (44"–58" Fitment) ...

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$22.79 - $64.80
$22.79 - $64.80
$22.79 - $64.80
$22.79
Pack of Abena Abri-Form adult diapers on a white background
$35.49 - $81.99
$35.49 - $81.99
$35.49 - $81.99
$35.49

Abri-Form™ Comfort L4 - Heavy Absorbency Incontinence Brief

in stock

Abena Abri-Form Comfort L4 Plastic Backed All-In-One Briefs Model: Abri-Form™ Comfort L4 Series (44"–60" Waist/Hip Fitment...

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$35.49 - $81.99
$35.49 - $81.99
$35.49 - $81.99
$35.49
$35.69 - $142.99
$35.69 - $142.99
$35.69 - $142.99
$35.69

Abena® Slip Premium L3 - Heavy Absorbency Incontinence Brief

in stock

Abena Slip Premium L3 All-In-One Disposable Briefs Model: Abena® Slip Premium L3 Series (39"–59" Hip Fitment) Avai...

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$35.69 - $142.99
$35.69 - $142.99
$35.69 - $142.99
$35.69
Packaging of Arena Slip Premium bladder protection pads with a single pad displayed on a white background.
$46.99 - $146.99
$46.99 - $146.99
$46.99 - $146.99
$46.99

Abena Slip Premium L4 - Heavy Absorbency Incontinence Briefs

in stock

Abena Slip Premium L4 All-In-One Disposable Briefs Model: Abena® Slip Premium L4 Series (39"–59" Hip Fitment) Avai...

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$46.99 - $146.99
$46.99 - $146.99
$46.99 - $146.99
$46.99
Pack of Abena Slip Premium bladder protection briefs on a white background
$54.99 - $199.00
$54.99 - $199.00
$54.99 - $199.00
$54.99

Abena Slip Flexi Fit - Heavy Absorbency Incontinence Brief- M/L

in stock

Abena Slip Flexi-Fit Premium Elastic Tabbed Briefs Model: Abena® Slip Flexi-Fit Premium Series Availability: In St...

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$54.99 - $199.00
$54.99 - $199.00
$54.99 - $199.00
$54.99
Pack of Abena Slip Premium large-XLarge briefs with a white background
$29.49 - $133.99
$29.49 - $133.99
$29.49 - $133.99
$29.49

Abena Slip Flexi Fit - Heavy Absorbency Incontinence Brief, Large/X-Large

in stock

Abena Slip Flexi-Fit Premium Elastic Tabbed Briefs Model: Abena® Slip Flexi-Fit Premium Series (Large / X-Large Dual-Size ...

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$29.49 - $133.99
$29.49 - $133.99
$29.49 - $133.99
$29.49
Pack of Abena Slip Premium large-X-large bladder protection briefs on a white background
$42.99 - $157.00
$42.99 - $157.00
$42.99 - $157.00
$42.99

Abena Slip Flexi Fit - Heavy Absorbency Incontinence Brief, Large/X-Large

in stock

Abena Slip Flexi-Fit Premium Elastic Tabbed Briefs Model: Abena® Slip Flexi-Fit Premium Series (Large / X-Large Dual-Size)...

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$42.99 - $157.00
$42.99 - $157.00
$42.99 - $157.00
$42.99
Package of Abena adult briefs
$29.79 - $157.99
$29.79 - $157.99
$29.79 - $157.99
$29.79

Abena Premium Pants L3 – Heavy Absorbency – Large (39"–55") – 2400 mL Capacity

in stock

Abena Pants Premium L3 Protective Pull-On Underwear Model: Abena® Pants Premium L3 Series (39"–55" Hip Fitment) Av...

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$29.79 - $157.99
$29.79 - $157.99
$29.79 - $157.99
$29.79
depends briefs
$26.21 - $79.99
$26.21 - $79.99
$26.21 - $79.99
$26.21

Depend Absorbent Underwear with EasyGrip Tabs – Large

in stock

Depend Absorbent Underwear with EasyGrip Tabs Model: Depend® Open-Style Protective Brief Series Product Style: Unisex ...

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$26.21 - $79.99
$26.21 - $79.99
$26.21 - $79.99
$26.21

Large adult incontinence briefs are one of the most in-demand sizes on the market — and for good reason. For caregivers, family members, and individuals looking for a reliable, well-fitting brief that moves comfortably with the body, the large size strikes the balance between a secure fit and everyday wearability. Whether you're managing a daily routine at home or on the go, our large brief collection has you covered.

At EnhDme, we carry large adult incontinence briefs from trusted brands known for consistent sizing, quality absorbent cores, and skin-friendly materials. Our collection spans a wide range of absorbency levels and styles — so whether you need light daytime protection or heavy overnight coverage, you'll find a product that fits your needs and your lifestyle.

Did you know? Large is the single most purchased size in the adult incontinence brief category across the United States, making it the size with the widest product availability — and the most options to choose from when it comes to absorbency, style, and brand.

Our large briefs are sized to fit waist and hip measurements of approximately 45"–58" depending on the brand — always check the individual product size guide before ordering to confirm the best fit. With features like breathable side panels, refastenable tab closures, wetness indicators, and odor control, you'll find options suited for every routine and preference. Orders over $95 ship free, making it easy to keep a reliable supply on hand.

What You'll Find in This Collection

  • Disposable tab-style briefs
  • Light absorbency daytime briefs
  • Moderate absorbency briefs
  • Heavy absorbency briefs
  • Overnight / extended-wear briefs
  • Breathable, cloth-like outer cover briefs
  • Odor-control briefs
  • Latex-free & sensitive skin options

🚚 Free shipping on orders over $95 — EnhDme

Large Adult Briefs

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